Ulrik Cordes

Seminars

Friday 26th September 2025
Armoring T-Cells Against Oxidative Stress Breaking Through the Solid Tumor Barrier for Adoptive Cell Therapies
1:00 pm
  • How Reactive Oxygen Species (ROS) impact the immune function of various immune effector cells
  • Ex vivo activation of the Nrf2 pathway triggers a strong protection of cytotoxic lymphocytes against oxidative stress
  • Perspectives for improving clinical efficacy in solid tumors for NK-, CAR-T cells and TIL therapybased approaches