Preventing Tumor Suppression: Multiplex Engineering for Durable CAR-T in GBM

• Contrasting potency-driven approaches with the targeted prevention of multi-axis suppression in solid tumors
• Engineering intrinsic CAR-T resilience through multiplex editing to preempt tumor-mediated downregulation
• Leveraging patient-derived organoids and AI-guided design to accelerate translation and improve predictability

Speakers:

Aaron Edwards

Co-Founder & Chief Executive Officer

KiraGen Bio