Utilizing Targeted Gene Editing to Engineer Durable T-Cell Therapies

• Identifying the biological process behind T-cell downregulation
• Identifying and targeting negative regulators of T-cell function to disrupt biological downregulation pathways and preserve potency
• Applying gene editing strategies to intrinsically enhance T-cell durability by preventing functional exhaustion and loss of therapeutic activity

Speakers:

Enrique Zudaire

Senior Vice President - Translational Sciences & Therapeutics Discovery

Caribou Biosciences