Leonardo Ferreira
Assistant Professor Torpedo Bio
Leonardo Ferreira is an Assistant Professor of Microbiology and Immunology and, by courtesy, of Regenerative Medicine and Cell Biology at the Medical University of South Carolina and the Hollings Cancer Center. As a postdoctoral scholar at the University of California San Francisco, he created an anti-HLA-A2 chimeric antigen receptor (CAR) and used CRISPR/Cas9-mediated gene knock-in to replace the endogenous T cell receptor gene with this CAR gene in primary human regulatory T cells. The resulting CAR Tregs were suppressive upon recognizing HLA-A2 and trafficked to transplanted human islets. His laboratory focuses on engineered immune receptors to develop new cellular therapies.