Peggy Sotiropoulou

Chief Scientific Officer T-knife GmbH

Dr. Peggy Sotiropoulou is the CSO of T-knife Therapeutics. She is a biotech leader with 25+ years advancing immuno-oncology and cell therapy programs from discovery to clinic. As CSO at T-knife Therapeutics, she leads the development of Supercharged T cell therapies for patients with solid tumors. Formerly Head of R&D at Celyad Oncology, Peggy developed scalable engineered CAR T cell therapy platforms. Prior to that, Peggy was tenured Associate Professor at Université Libre de Bruxelles, leading research on the response and sensitization of recalcitrant tumors to therapy. Peggy holds a PhD in Cancer Immunology from the University of Crete and an MSc in Biological Sciences from the University of Athens.

Seminars

Tuesday 15th September 2026
Designing In Vivo T-Cell Therapies to Combat Resistance & Enhance Durability in Solid Tumors
11:30 am
  • Identifying mechanisms of resistance to understand impact in vivo CAR-T durability
  • Balancing armored CAR/TCR designs to optimize long-term efficacy while minimizing safety risks
  • Evaluating in vivo therapeutic approaches for treating solid tumors in complex tumor microenvironments
Peggy Sotiropoulou - T-Knife Therapeutics - Expert Speaker at the 11th CAR-TCR Summit 2026