Panel Discussion: Selecting Gene Editing Strategies to Prevent Downregulation & Enhance Cell Therapy Outcomes
- Compare knockout, base editing, and prime editing approaches to guide technology selection
- Evaluating alternative strategies such as gene silencing and expression modulation, to reduce biological risk while preserving functional benefit across indications
- Assessing the impact of editing strategies on genomic integrity and patient safety to balance therapeutic enhancement with longterm DNA health and regulatory confidence